Alzheimer’s Disease Risk DNA Test
Does late-onset Alzheimer’s disease run in your family? Discover your genetic predisposition to Alzheimer’s disease with the DNA Family Check Alzheimer’s Disease Risk DNA Test Kit.
- Examines APOE variants (e2, e3, and e4) linked to an increased risk of Alzheimer’s disease
- Understand your genetic risk to make informed decisions about your future health
- Simple, at-home sample collection with painless mouth swabs
Take the first step towards understanding your genetic risk for Alzheimer’s Disease.
The APOE gene plays a multifaceted role in the body. It is vital for transporting fats, supporting neuronal growth and nerve regeneration, regulating immune responses, and repairing injuries in the central nervous system. These functions are especially important in brain health and are linked to the development of Alzheimer’s disease.
Genetic Variants Analyzed in the Test:
The test analyzes three common alleles of the APOE gene: e2, e3, and e4. Everyone inherits two copies of the APOE gene, one from each parent. The combination of these alleles determines an individual’s genetic risk for Alzheimer’s disease:
- e2/e2 & e2/e3: These combinations are associated with a reduced risk of developing Alzheimer’s disease.
- e2/e4 & e3/e4: Individuals with these combinations have approximately a 3-fold increased risk of developing Alzheimer’s disease.
- e3/e3: This combination is linked to no additional risk or reduction in the risk of Alzheimer’s disease.
- e4/e4: Carrying two copies of the e4 allele significantly increases the risk, with a 10- to 15-fold higher likelihood of developing Alzheimer’s disease.
Understanding your specific APOE genotype can be instrumental in early detection and proactive management of Alzheimer’s disease. Identifying a higher genetic risk can prompt earlier and more frequent monitoring, and potential lifestyle changes.