Thrombotic Risk DNA Test
$195.00
The Thrombotic Risk DNA Test evaluates your genetic risk for thrombophilia by analyzing key mutations in the F5, F2, and MTHFR genes. These mutations are associated with an increased risk of abnormal blood clot formation, which can lead to serious health complications if not properly managed.
- Identify F5, F2, and MTHFR gene mutations linked to thrombotic risk.
- Non-invasive cheek swab collection from home.
- Secure and private online access to your results.
Summary
What is Thrombosis?
Thrombosis refers to the formation of a blood clot (thrombus) within a blood vessel, obstructing the flow of blood through the circulatory system. The consequences of thrombosis can be severe, potentially leading to life-threatening conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), heart attack, or stroke.
The risk of developing thrombosis is influenced by various factors, including genetic predisposition, lifestyle choices, and certain medical conditions.
The Genetics of Thrombosis
The Thrombotic Risk DNA Test analyzes specific genetic variants known to influence blood clotting and thrombotic risk. These genetic markers impact how the blood coagulates, the regulation of clot formation, and how the body breaks down clots once they form. Individuals with certain genetic variations may have a heightened risk of developing dangerous blood clots, particularly when combined with environmental risk factors such as long periods of inactivity (e.g., long-haul flights), surgery, or hormone therapy.
DNA Thrombotic Risk Test
The DNA Thrombotic Risk Test focuses on three key genes that play important roles in the blood clotting process:
- F5 (Factor V Leiden): The F5 gene provides instructions for making a protein called Factor V, which is essential for blood clotting. A specific mutation in this gene, known as Factor V Leiden, makes Factor V resistant to inactivation. This can lead to a prolonged clotting process and an increased risk of blood clot formation.
- F2 (Prothrombin G20210A): The F2 gene encodes prothrombin, another protein involved in blood clotting. The G20210A mutation in this gene can lead to elevated prothrombin levels, which can also increase the risk of blood clot formation.
- MTHFR (C677T and A1298C): The MTHFR gene provides instructions for making an enzyme involved in folate metabolism. The C677T and A1298C mutations in the MTHFR gene can lead to reduced enzyme activity and elevated homocysteine levels, which are associated with an increased risk of blood clots.
Test Procedure and Interpretation of Results
The Thrombotic Risk DNA Test is a simple cheek swab test that detects the presence of the F5, F2, and MTHFR variants. The results indicate whether you carry one or more of these variants, offering insights into your risk for developing thrombosis.
Single Variant Carriers: Individuals carrying one copy of a variant like Factor V Leiden or the prothrombin G20210A mutation are at an increased risk for thrombosis. Combining genetic predisposition with environmental factors can further elevate the risk.
Multiple Variants Carriers: Carriers of multiple variants are at significantly higher risk. For example, an individual with both the Factor V Leiden variant and the prothrombin mutation faces a much greater cumulative risk.
Homozygous Carriers: Those with two copies of the same variant, such as homozygous carriers of Factor V Leiden, are at an especially high risk of developing thrombotic events. Careful monitoring and preventive measures may be required in high-risk situations such as surgery or pregnancy.
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Why DNA Family Check?
With over 20 years of experience and a proven track record, DNA Family Check is the trusted leader in relationship DNA testing. Our high-volume accredited laboratory has helped millions of families worldwide find answers and resolve questions about their relationships. As pioneers in the industry, we were one of the first to introduce the easy cheek swab method that's now the industry standard.
With our longstanding commitment to excellence and innovation, it's no wonder we're America's #1 choice for paternity answers. Our accredited laboratory is dedicated to providing accurate, reliable, and confidential results, ensuring that families receive the truth they need to move forward. With DNA Family Check, you can trust that you're in good hands.
